Improving the way small molecules are made using transition metals.
Improving Small Molecule Synthesis by Controlling Reactions between Transition Metals and Carbon-Heteroatom Electrophiles
This study is working on making it easier and more efficient to create small molecules that are important for developing new medicines, by improving the way certain chemical reactions happen.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Montana State University - Bozeman NIH-funded |
| Lab location | 1 site (Bozeman, United States) |
| Project ID | NIH-10857277 on NIH RePORTER |
What this research studies
This research focuses on enhancing the synthesis of small molecules, which are crucial for biomedical applications, by improving the control over reactions involving transition metals and carbon-heteroatom electrophiles. The team will address challenges in the catalytic process, particularly during the oxidative addition step, which is essential for forming carbon-carbon and carbon-nitrogen bonds. By employing both experimental techniques and computational methods, the research aims to develop more efficient and selective catalytic reactions, ultimately facilitating the creation of important pharmacological compounds.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals involved in drug development or those requiring new therapeutic compounds.
Not a fit: Patients who are not involved in drug development or do not require new pharmacological treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more efficient methods for producing small molecules that are vital for drug discovery and development.
How similar studies have performed: Previous research has shown promise in improving catalytic methods for small molecule synthesis, indicating that this approach has potential for success.
Where this research is happening
Bozeman, United States
- Montana State University - Bozeman — Bozeman, United States (Active)
Researchers
- Principal investigator: Neufeldt, Sharon — Montana State University - Bozeman
- Study coordinator: Neufeldt, Sharon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.