Improving the use of long-acting injectable HIV prevention
Official title: Optimizing implementation of long-acting injectable PrEP
Funded at Medical College of Wisconsin · NIH-10924590 · Data updated 2026-11-12
This study is looking at how to make it easier for doctors to offer a new HIV prevention shot that you get every eight weeks, especially for Black men and transgender women who are at higher risk, so that more people can access this helpful treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $702,000 |
| NIH project number | 1R34MH135746-01A1 |
| Project ID | NIH-10924590 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at high risk for HIV, particularly Black cisgender men and transgender women who have sex with men.
✕Less likely to help
Patients who are not at risk for HIV or those who do not have access to healthcare facilities offering LAI-PrEP may not benefit from this research.
What this research studies
This research focuses on enhancing the implementation of long-acting injectable pre-exposure prophylaxis (LAI-PrEP) for HIV prevention, which is administered via an intramuscular injection every eight weeks. The study aims to identify barriers to prescribing this innovative treatment, particularly among healthcare providers, and to understand how it can be effectively integrated into clinical practice. By addressing these challenges, the research seeks to improve access to LAI-PrEP for populations at higher risk of HIV, including Black cisgender men and transgender women. The approach involves collaboration with communities and healthcare facilities to ensure that the treatment meets the needs of those it aims to protect.
Why it matters
Potential benefit: If successful, this research could significantly increase the availability and use of LAI-PrEP, leading to reduced HIV incidence among vulnerable populations.
How similar studies have gone: Other research has shown promise in improving HIV prevention strategies, but the specific implementation of LAI-PrEP is relatively novel and requires further exploration.
Where this research is happening
-
Medical College of Wisconsin
Milwaukee, United States Active
Researchers
- Principal investigator: John, Steven a — Medical College of Wisconsin
- Study coordinator: John, Steven a
Related research
Other NIH-funded projects on the same topics.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
-
Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
-
TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.