Improving the use of hydroxyurea for sickle cell disease in Nigeria

mAnaging siCkle CELl disease through incReased AdopTion of hydroxyurEa in Nigeria (ACCELERATE)

NIH-funded research New York University · NIH-10907044

This study is working to help more people with sickle cell disease in Nigeria get the medicine hydroxyurea, which can really improve their health and reduce serious problems, by making it easier for doctors to prescribe and manage the treatment.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionNew York University NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10907044 on NIH RePORTER

What this research studies

This research focuses on increasing the adoption of hydroxyurea (HU) treatment for sickle cell disease (SCD) in Nigeria, where many patients currently lack access to effective care. The project aims to address barriers that prevent healthcare providers from prescribing HU, which has been shown to reduce complications and mortality associated with SCD. By implementing a structured approach that includes screening, treatment initiation, and ongoing management, the research seeks to enhance patient outcomes through better healthcare practices. The study will utilize evidence-based guidelines and algorithms to facilitate the adoption of HU in clinical settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with sickle cell disease living in Nigeria.

Not a fit: Patients with sickle cell disease who are already receiving effective treatment or those living outside Nigeria may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the health and quality of life for patients with sickle cell disease in Nigeria by increasing access to effective treatment.

How similar studies have performed: Previous research has demonstrated success in similar approaches to increasing treatment adoption for sickle cell disease in other regions, indicating potential for positive outcomes in this study.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.