Improving the use of genetic data to understand health and disease
Methods to enable robust and efficient use of genetic summary data
This study is working on improving how we understand genetic information to help everyone, especially those from underrepresented backgrounds, get better insights into their health and diseases, which could lead to more personalized treatment options for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10880664 on NIH RePORTER |
What this research studies
This research focuses on enhancing the analysis of publicly available genetic summary data to better understand the genetic factors that contribute to health and disease. It aims to develop methods that allow researchers to effectively utilize genetic data, particularly for underrepresented ancestral groups, ensuring equitable access to genetic insights. By addressing issues of data heterogeneity and confounding factors, the research seeks to improve the accuracy of genetic analyses, including polygenic risk scores and causal variant prioritization. Patients may benefit from more precise genetic insights that can inform personalized treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals from diverse ancestral backgrounds, particularly those from underrepresented groups in genetic studies.
Not a fit: Patients with conditions that are not influenced by genetic factors may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate genetic assessments and personalized healthcare strategies for patients.
How similar studies have performed: Other research has shown success in utilizing genetic summary data for health insights, but this approach aims to address specific gaps in representation and data analysis methods.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Hendricks, Audrey E — University of Colorado Denver
- Study coordinator: Hendricks, Audrey E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.