Improving the taste of pediatric medicines using bitter taste receptor blockers
Official title: Expertise in Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines: Trained Human Sensory Panels
Funded at Advanced Bioscience Laboratories, INC. · NIH-11164990 · Data updated 2026-11-12
This study is all about making medicines taste better for kids, especially those with HIV, by using special blockers to reduce bitterness, so they’re more likely to take their medicine without fuss.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Advanced Bioscience Laboratories, INC. NIH-funded |
| Lab location | 1 site (Kensington, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $807,060 |
| NIH project number | 75N93023D00001-0-759302400002-1 |
| Project ID | NIH-11164990 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children who require medication for HIV or related conditions and may struggle with the taste of their current treatments.
✕Less likely to help
Patients who do not require medication for HIV or related conditions, or those who have no issues with the taste of their current medications, may not benefit from this research.
What this research studies
This research focuses on enhancing the palatability of medicines for children by utilizing bitter taste receptor blockers. The approach involves trained human sensory panels to evaluate and improve the taste of pediatric formulations, making them more acceptable for young patients. By addressing the challenge of medicine taste, the research aims to increase adherence to treatment regimens among children, particularly those at risk for or living with HIV. The methodology includes sensory evaluation and product development to create more appealing medicinal options.
Why it matters
Potential benefit: If successful, this research could lead to more palatable pediatric medicines, improving medication adherence and health outcomes for children.
How similar studies have gone: Previous research has shown success in improving medication adherence through taste modification strategies, indicating potential for this approach.
Where this research is happening
-
Advanced Bioscience Laboratories, INC.
Kensington, United States Active
Researchers
- Principal investigator: Silvera, Peter — Advanced Bioscience Laboratories, INC.
- Study coordinator: Silvera, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.