Improving the taste of pediatric medicines using bitter taste receptor blockers
Official title: Expertise in Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines: Blocker Discovery
Funded at Advanced Bioscience Laboratories, INC. · NIH-11142352 · Data updated 2026-11-12
This study is working on making medicines for kids taste better by using special blockers to reduce bitterness, so that children will be more willing to take their medicine and stick to their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Advanced Bioscience Laboratories, INC. NIH-funded |
| Lab location | 1 site (Kensington, United States) |
| Project start | April 15, 2023 |
| Project end | April 14, 2030 |
| Funding year | 2024 |
| Award (this year) | $1,324,494 |
| NIH project number | 75N93023D00001-0-759302400001-1 |
| Project ID | NIH-11142352 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children who need to take medications that currently have unpleasant tastes.
✕Less likely to help
Patients who are not pediatric or those who do not require medication that is difficult to ingest due to taste may not benefit from this research.
What this research studies
This research focuses on enhancing the palatability of medicines for children by utilizing bitter taste receptor blockers. The approach involves developing new formulations that make medications more acceptable to pediatric patients, which is crucial for adherence to treatment regimens. By collaborating with various scientific and academic partners, the project aims to advance the development of these improved medicines through preclinical testing and regulatory pathways. The ultimate goal is to ensure that children can receive necessary treatments without the aversion caused by unpleasant tastes.
Why it matters
Potential benefit: If successful, this research could lead to more palatable pediatric medications, improving adherence and health outcomes for children requiring treatment.
How similar studies have gone: Previous research has shown promise in improving medication adherence through taste masking techniques, indicating that this approach could be effective.
Where this research is happening
-
Advanced Bioscience Laboratories, INC.
Kensington, United States Active
Researchers
- Principal investigator: Silvera, Peter — Advanced Bioscience Laboratories, INC.
- Study coordinator: Silvera, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.