Improving the success of stem cell-derived pancreatic islet transplants
Official title: Monitoring and increasing resilience of stem cell derived pancreatic islet cell grafts
Funded at Minutia, INC. · NIH-10922479 · Data updated 2026-11-12
This study is looking at ways to make stem cell transplants for type 1 diabetes work better and last longer, so people with the condition might need less insulin and have better blood sugar control.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Minutia, INC. NIH-funded |
| Lab location | 1 site (Oakland, United States) |
| Project start | July 20, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $324,998 |
| NIH project number | 1R43DK138729-01A1 |
| Project ID | NIH-10922479 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with type 1 diabetes who may benefit from pancreatic islet transplantation.
✕Less likely to help
Patients with type 2 diabetes or those who are not candidates for islet transplantation may not receive benefits from this research.
What this research studies
This research focuses on enhancing the resilience of pancreatic islet cell grafts derived from stem cells, which are crucial for treating type 1 diabetes (T1D). The project aims to address the challenges faced by these grafts, such as the need for immunosuppression and the inflammatory environment at the transplant site. By investigating new methods to monitor and improve the function of these grafts, the research seeks to provide a more effective treatment option for individuals with T1D. Patients may benefit from a potential reduction in the need for insulin management and improved metabolic control.
Why it matters
Potential benefit: If successful, this research could lead to more effective and sustainable treatments for type 1 diabetes, potentially reducing or eliminating the need for insulin therapy.
How similar studies have gone: Previous research has shown promise in using stem cell-derived islets for transplantation, indicating a potential breakthrough in treatment options for type 1 diabetes.
Where this research is happening
-
Minutia, INC.
Oakland, United States Active
Researchers
- Principal investigator: Digovich, Catherine — Minutia, INC.
- Study coordinator: Digovich, Catherine
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.