Improving the storage and shelf life of red blood cells
An Improved Red Blood Cell Storage Product and Extended Shelf Life using a Normoglycemic Additive Solution
This study is looking at a new way to store red blood cells to keep them healthier and usable for longer, which could help make sure there’s always safe blood available for transfusions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10877043 on NIH RePORTER |
What this research studies
This research investigates a new method for storing red blood cells (RBCs) that aims to enhance their viability and extend their shelf life. The approach involves using a normoglycemic additive solution, which maintains blood glucose levels similar to those found in healthy individuals, potentially reducing damage to the RBCs during storage. The study will also explore a rejuvenating solution based on C-peptide to further improve the quality of stored blood. By addressing current storage limitations, this research seeks to ensure a more reliable supply of safe blood for transfusions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who require blood transfusions, such as those undergoing surgery, trauma patients, or individuals with certain medical conditions.
Not a fit: Patients who do not require blood transfusions or those with conditions that contraindicate transfusion may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective blood transfusions for patients in need.
How similar studies have performed: Previous research has shown promise in improving blood storage techniques, but this specific approach using normoglycemic conditions is relatively novel.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Spence, Dana M — Michigan State University
- Study coordinator: Spence, Dana M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.