Improving the stability of vaccines using natural solvents
Official title: Enhancing Vaccine Thermostability with Natural Deep Eutectic Solvents
Funded at College at Oswego · NIH-11084835 · Data updated 2026-11-12
This study is looking at how special natural solvents can help keep viral vaccines effective even when they’re stored in tough temperature conditions, making it easier to get vaccines to people who need them.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | College at Oswego NIH-funded |
| Lab location | 1 site (Oswego, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $13,390 |
| NIH project number | 3R15GM153057-01S1 |
| Project ID | NIH-11084835 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals in areas where vaccine storage and distribution are challenging due to temperature fluctuations.
✕Less likely to help
Patients who live in regions with reliable vaccine storage and distribution systems may not see direct benefits from this research.
What this research studies
This research focuses on enhancing the thermostability of viral vaccines by utilizing natural deep eutectic solvents. The approach involves studying how these solvents can improve the storage and distribution of vaccines, particularly in challenging environments. By ensuring that vaccines remain effective even under varying temperature conditions, this research aims to facilitate better vaccine deployment and accessibility. The project is supported by the acquisition of a specialized ultralow freezer to maintain the necessary biological materials for these studies.
Why it matters
Potential benefit: If successful, this research could lead to more stable vaccines that are easier to distribute and administer, particularly in regions with extreme temperatures.
How similar studies have gone: Other research has shown promise in using novel solvents to enhance vaccine stability, indicating a potential for success in this approach.
Where this research is happening
-
College at Oswego
Oswego, United States Active
Researchers
- Principal investigator: Mirjafari, Arsalan — College at Oswego
- Study coordinator: Mirjafari, Arsalan
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This study is working on new ways to keep vaccines stable so they can be stored at room temperature, making it easier to get them to people in areas that don’t have refrigeration, especially for vaccines like those for yellow fever and adenoviruses.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.