Improving the stability of biosensors for better disease monitoring
Breakthrough Blocking-Layer Stability for Broader Clinical Utility of Continuous Aptamer Biosensors
This study is working on making special sensors that can track important health markers in real-time, like heart health and fertility, so that patients can get better and more personalized care.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cincinnati NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10888235 on NIH RePORTER |
What this research studies
This research focuses on enhancing the longevity and reliability of electrochemical aptamer-based sensors, which can monitor various molecules in real-time for conditions like cardiac health and fertility. The team aims to understand the degradation mechanisms of these sensors in biological fluids, which has previously limited their use. By improving the stability of these sensors, the research seeks to enable continuous monitoring for a wider range of health conditions beyond glucose levels. Patients may benefit from more effective and personalized disease management through these advanced biosensors.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions requiring continuous monitoring, such as diabetes, cardiac issues, or fertility challenges.
Not a fit: Patients who do not require real-time monitoring of biochemical markers or those with stable conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more reliable and versatile biosensors that improve real-time health monitoring for various conditions.
How similar studies have performed: Previous research has shown promise in the development of electrochemical aptamer-based sensors, but this specific approach to enhancing stability is relatively novel.
Where this research is happening
Cincinnati, United States
- University of Cincinnati — Cincinnati, United States (Active)
Researchers
- Principal investigator: Heikenfeld, Jason — University of Cincinnati
- Study coordinator: Heikenfeld, Jason
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.