Improving the speed of treatment for prolonged seizures in children
Official title: Quality Improvement in time to Treatment of Status Epilepticus (QuITT-SE)
Funded at Research Inst Nationwide Children's Hosp · NIH-10932198 · Data updated 2026-11-12
This study is working to make sure that children with prolonged seizures get the right treatment faster by using a set of helpful steps in hospitals, so they can recover better and stay safe.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $627,909 |
| NIH project number | 5R01NS133037-02 |
| Project ID | NIH-10932198 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who experience acute seizures that may lead to status epilepticus.
✕Less likely to help
Patients who do not experience seizures or are older than 11 years may not benefit from this research.
What this research studies
This research focuses on enhancing the timely treatment of status epilepticus (SE) in children, which is a serious condition characterized by prolonged or repeated seizures. The study aims to implement a standardized set of quality improvement (QI) interventions across various pediatric hospitals to ensure that children receive the appropriate benzodiazepine treatment quickly. By examining the effects of these interventions, the research seeks to reduce the time it takes to treat SE, ultimately aiming to decrease the associated risks of morbidity and mortality. The approach includes a hybrid design that evaluates both the effectiveness of the interventions and how well they can be implemented in different healthcare settings.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of severe outcomes from status epilepticus in children by ensuring faster treatment.
How similar studies have gone: Previous studies have shown success in improving treatment times for status epilepticus through quality improvement interventions, indicating that this approach has potential.
Where this research is happening
-
Research Inst Nationwide Children's Hosp
Columbus, United States Active
Researchers
- Principal investigator: Ostendorf, Adam P. — Research Inst Nationwide Children's Hosp
- Study coordinator: Ostendorf, Adam P.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.