Improving the speed of treatment for prolonged seizures in children

Quality Improvement in time to Treatment of Status Epilepticus (QuITT-SE)

NIH-funded research Research Inst Nationwide Children's Hosp · NIH-10932198

This study is working to make sure that children with prolonged seizures get the right treatment faster by using a set of helpful steps in hospitals, so they can recover better and stay safe.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Inst Nationwide Children's Hosp NIH-funded
Lab location1 site (Columbus, United States)
Project IDNIH-10932198 on NIH RePORTER

What this research studies

This research focuses on enhancing the timely treatment of status epilepticus (SE) in children, which is a serious condition characterized by prolonged or repeated seizures. The study aims to implement a standardized set of quality improvement (QI) interventions across various pediatric hospitals to ensure that children receive the appropriate benzodiazepine treatment quickly. By examining the effects of these interventions, the research seeks to reduce the time it takes to treat SE, ultimately aiming to decrease the associated risks of morbidity and mortality. The approach includes a hybrid design that evaluates both the effectiveness of the interventions and how well they can be implemented in different healthcare settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who experience acute seizures that may lead to status epilepticus.

Not a fit: Patients who do not experience seizures or are older than 11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of severe outcomes from status epilepticus in children by ensuring faster treatment.

How similar studies have performed: Previous studies have shown success in improving treatment times for status epilepticus through quality improvement interventions, indicating that this approach has potential.

Where this research is happening

Columbus, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.