Improving the sharing of genomic data while protecting privacy
Official title: Accelerating Genomic Data Sharing and Collaborative Research with Privacy Protection
Funded at Case Western Reserve University · NIH-11105905 · Data updated 2026-11-12
This study is working on a safe way for researchers to share and analyze genetic information so they can collaborate better while keeping your personal details private.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $632,251 |
| NIH project number | 5R01LM014520-03 |
| Project ID | NIH-11105905 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have participated in genomic studies and are concerned about the privacy of their genetic information.
✕Less likely to help
Patients who are not involved in genomic studies or do not have a vested interest in genomic data sharing may not benefit from this research.
What this research studies
This research focuses on enhancing the sharing of genomic data among researchers while ensuring the privacy of participants is maintained. It aims to create a collaborative environment where researchers can preview their data analyses without compromising sensitive information. By developing a sandbox framework, the project allows for the rectification of datasets and generation of collaborative results in a secure manner. This approach addresses the challenges of data access and quality in genomic studies, ultimately facilitating more effective research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and therapies by enabling broader access to high-quality genomic data.
How similar studies have gone: Other research has shown promise in developing privacy-preserving data sharing methods, indicating that this approach could be effective.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Ayday, Erman — Case Western Reserve University
- Study coordinator: Ayday, Erman
Related research
Other NIH-funded projects on the same topics.
-
Estrogen signaling and how the intestinal lining protects against injury
A study at Case Western Reserve University looks at how estrogen receptors in the gut lining help protect against intestinal injury and inflammatory bowel disease.
-
Diabetes: Long-term effects of intensive glucose control on complications
A long-term study follows adults with type 1 diabetes to see how keeping blood sugar close to normal affects eye, kidney, nerve, heart, and quality of life outcomes over many years.
-
Epidemiology of Diabetes Interventions and Complications (EDIC) Study follow-up
This long-term study follows adults with type 1 diabetes to see how early intensive glucose control affects complications and quality of life over many years.
-
Role of THAP1 in brain cell support cells shaping brain development
Aims to understand how the THAP1 protein in oligodendrocyte lineage cells helps shape the brain’s environment and myelination during development, which may relate to a movement disorder called DYT6 dystonia.
-
New human monoclonal antibodies to stop malaria caused by Plasmodium vivax
A researcher team is developing human monoclonal antibodies to prevent and treat malaria from Plasmodium vivax, with a plan to test promising antibodies in primates and prepare for human trials.
-
PopCASE: A user-friendly tool to link cancer data for communities and researchers
Aimed at improving population cancer research, PopCASE helps connect patient cancer data with community information to inform better care and outreach.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.