Improving the safety of devices used to treat brain aneurysms
Enhanced endothelialization of nanomatrix coated flow diverter for intracranial aneurysms
['FUNDING_SBIR_2'] · ENDOMIMETICS, LLC · NIH-11008596
This study is testing a new type of flow diverter for people with unruptured cerebral aneurysms, which has a special coating to help heal faster and reduce risks like blood clots, making treatment safer and more effective.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ENDOMIMETICS, LLC (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-11008596 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing a device called a flow diverter, which is used to treat unruptured cerebral aneurysms. The device is coated with a special material that mimics the natural lining of blood vessels, promoting faster healing and reducing complications. By releasing nitric oxide, the coating helps attract and retain the cells necessary for healing, potentially leading to quicker closure of the aneurysm. This approach aims to minimize the risks associated with current treatments, such as blood clots and bleeding.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with unruptured cerebral aneurysms who may require treatment to prevent rupture.
Not a fit: Patients with ruptured cerebral aneurysms or those who do not have aneurysms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for patients with cerebral aneurysms, reducing the risk of rupture and improving recovery outcomes.
How similar studies have performed: Previous research has shown promise in using similar coating technologies to enhance medical devices, indicating potential for success in this novel approach.
Where this research is happening
BIRMINGHAM, UNITED STATES
- ENDOMIMETICS, LLC — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHERWOOD, JENNIFER — ENDOMIMETICS, LLC
- Study coordinator: SHERWOOD, JENNIFER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.