Improving the safety and effectiveness of implanted neuromodulation electrodes
Official title: Development and In Vivo Validation of a Theoretical Framework and Practical Methods to Improve Safety and Efficacy of Neuromodulation Electrodes
Funded at University of Wisconsin-Madison · NIH-10572029 · Data updated 2026-11-12
This study is working on improving the safety and effectiveness of tiny electrodes used in treatments that help with conditions like chronic pain or movement disorders, so that patients can have better experiences and results from their therapies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,146,270 |
| NIH project number | 1RF1NS129955-01 |
| Project ID | NIH-10572029 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who may benefit from implanted neuromodulation therapies, such as those with chronic pain or movement disorders.
✕Less likely to help
Patients who do not require or are not candidates for neuromodulation therapies may not receive any benefit from this research.
What this research studies
This research focuses on enhancing the safety and efficacy of electrical stimulation through implanted electrodes. It aims to develop a new framework and practical methods for testing these electrodes, which have been limited by outdated approaches. By validating and optimizing a benchtop testing framework, the research seeks to predict chronic safety issues more accurately, particularly for advanced microelectrode designs and novel stimulation techniques. This could lead to better outcomes for patients receiving neuromodulation therapies.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective neuromodulation therapies for patients.
How similar studies have gone: Other research has shown promise in improving electrode safety and efficacy, but this approach aims to address gaps in current methodologies, making it a novel effort.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Ludwig, Kip a — University of Wisconsin-Madison
- Study coordinator: Ludwig, Kip a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.