NIH-funded research R01 grant

Improving the reliability of simplified medical information using AI language models

Official title: Building Safety Guards into LLMs for Trustworthy Automatic Simplification of Medical Documents

Funded at University of Texas at Austin · NIH-10944659 · Data updated 2026-11-12

This study is working on making medical information easier to understand and more reliable by using advanced technology to spot mistakes in simplified texts, so everyone can access trustworthy health knowledge and feel more confident about their health decisions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin
NIH-funded
Lab location1 site (Austin, United States)
Project startSeptember 18, 2024
Project endAugust 31, 2028
Funding year2024
Award (this year)$363,790
NIH project number1R01LM014600-01
Project IDNIH-10944659 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include individuals seeking reliable medical information in simpler language, particularly those with limited health literacy.

Less likely to help

Patients who are already well-versed in medical terminology and have access to peer-reviewed literature may not find this research beneficial.

What this research studies

This research aims to enhance the accuracy and reliability of simplified medical documents generated by large language models (LLMs) like ChatGPT. It focuses on developing new natural language processing technologies that can detect errors in the simplified texts, ensuring that the information provided to the public is both accessible and trustworthy. By creating tools that help communities critically evaluate LLM outputs, the project seeks to improve health literacy and empower individuals with better access to medical knowledge. The approach includes building controllable and transparent LLMs that can safely simplify complex medical literature.

Why it matters

Potential benefit: If successful, this research could provide patients and the general public with more accurate and understandable medical information, enhancing their ability to make informed health decisions.

How similar studies have gone: While the use of LLMs for simplifying medical texts is a novel approach, there have been successful applications of AI in other areas of healthcare communication.

Where this research is happening

  • University of Texas at Austin
    Austin, United States
    Active

Researchers

  • Principal investigator: Li, Junyi Jessy — University of Texas at Austin
  • Study coordinator: Li, Junyi Jessy

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.