Improving the reliability of research using the C. elegans model organism
Official title: EleGantry: a software and hardware infrastructure to improve rigor and reproducibility within invertebrate research
Funded at Ora Biomedical, INC. · NIH-11006951 · Data updated 2026-11-12
This study is working on making experiments with tiny worms called Caenorhabditis elegans more consistent and reliable, which could help scientists better understand aging and related health issues that might benefit people in the long run.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ora Biomedical, INC. NIH-funded |
| Lab location | 1 site (Tukwila, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $324,240 |
| NIH project number | 1R43OD037622-01A1 |
| Project ID | NIH-11006951 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals interested in the biological mechanisms of aging and those affected by age-related diseases.
✕Less likely to help
Patients with conditions unrelated to aging or neurological function may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the rigor and reproducibility of experiments involving the model organism Caenorhabditis elegans, commonly used in studies of aging and neuronal function. The project aims to address the significant variability in lifespan data reported in previous studies by developing a software and hardware infrastructure that standardizes experimental conditions and improves data collection. By minimizing sources of variance and ensuring comprehensive reporting, the research seeks to create a more reliable framework for future studies. Patients may benefit indirectly through advancements in understanding aging and related diseases.
Why it matters
Potential benefit: If successful, this research could lead to more consistent and reliable findings in studies related to aging and neurological conditions, ultimately improving therapeutic strategies.
How similar studies have gone: Other research has shown success in improving experimental methodologies in biological studies, suggesting that this approach could yield valuable advancements.
Where this research is happening
-
Ora Biomedical, INC.
Tukwila, United States Active
Researchers
- Principal investigator: Lee, Mitchell Brendon — Ora Biomedical, INC.
- Study coordinator: Lee, Mitchell Brendon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.