Improving the recognition of sepsis in infants

Situation Awareness to Improve Infant Sepsis Recognition in the Presence of Clinical Uncertainty

NIH-funded research Children's Hosp of Philadelphia · NIH-10821444

This study is working on a new system to help doctors and nurses spot sepsis in babies earlier, so they can get the right treatment quickly and stay healthy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChildren's Hosp of Philadelphia NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10821444 on NIH RePORTER

What this research studies

This research aims to enhance the early detection of sepsis in infants, a condition that can lead to severe complications and high mortality rates. By developing an innovative early recognition system that integrates patient data with predictive modeling, the project seeks to provide healthcare professionals with timely and accurate information. The approach involves utilizing existing neonatal sepsis registry data and advanced clinical informatics to improve situation awareness among clinicians and nurses. The goal is to ensure that infants at the highest risk for sepsis receive prompt and effective treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants who are at risk for sepsis, particularly those admitted to neonatal intensive care units.

Not a fit: Patients who are not infants or those who do not exhibit risk factors for sepsis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce mortality and long-term health issues associated with sepsis in infants.

How similar studies have performed: Previous research has shown promise in using predictive modeling and clinical informatics to improve disease recognition, suggesting that this approach could be effective.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.