Improving the quality of life for prostate cancer survivors with low testosterone levels

Improving Quality of Life of Prostate Cancer Survivors with Androgen Deficiency

NIH-funded research Brigham and Women's Hospital · NIH-10398005

This study is looking at how testosterone replacement therapy might help men who have survived prostate cancer feel better and improve their energy and sexual health, and it's designed for those dealing with low testosterone levels after treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10398005 on NIH RePORTER

What this research studies

This research investigates how testosterone replacement therapy can enhance the quality of life for men who have survived prostate cancer and are experiencing symptoms like sexual dysfunction and low energy due to androgen deficiency. The study will involve a double-blind, placebo-controlled trial to assess the safety and effectiveness of testosterone therapy in these patients. Participants will be monitored for improvements in sexual function and overall health-related quality of life. The goal is to provide evidence-based treatment options for prostate cancer survivors facing these challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are men who have undergone radical prostatectomy for prostate cancer and are experiencing symptoms related to low testosterone levels.

Not a fit: Patients who do not have a history of prostate cancer or those who are not experiencing symptoms of androgen deficiency may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the sexual function and overall well-being of prostate cancer survivors suffering from androgen deficiency.

How similar studies have performed: Previous open-label trials have suggested that testosterone replacement therapy may be safe for prostate cancer survivors, but this research aims to provide more definitive evidence through a randomized trial.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.