Improving the production of patient-specific stem cells for therapy
Official title: EFFICIENT SCALE-UP OF IPS CELLS FOR AUTOLOGOUS CELL THERAPY WORKFLOW
Funded at Link Biosystems INC. · NIH-10822298 · Data updated 2026-11-12
This study is working on a better way to grow special stem cells that can be used in personalized treatments for patients, making it easier and more affordable to produce the large amounts needed for therapy.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Link Biosystems INC. NIH-funded |
| Lab location | 1 site (Irvington, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $275,627 |
| NIH project number | 1R43CA285143-01A1 |
| Project ID | NIH-10822298 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who require personalized cell therapies, particularly those with conditions that can be treated using stem cell-based approaches.
✕Less likely to help
Patients who do not require cell therapy or those whose conditions cannot be addressed with stem cell treatments may not benefit from this research.
What this research studies
This research focuses on developing a more efficient method for expanding induced pluripotent stem cells (iPS cells) to create sufficient quantities for autologous cell therapies. It aims to design bioreactors that can grow these cells from a small initial population to clinically relevant doses while ensuring the process is cost-effective and suitable for clinical use. The approach utilizes a specialized serum-free media and controlled aggregation techniques to enhance cell growth and functionality, ultimately aiming to make personalized cell therapies more accessible to patients.
Why it matters
Potential benefit: If successful, this research could enable more effective and personalized cell therapies for patients, improving treatment outcomes.
How similar studies have gone: Previous research has shown promise in similar approaches to cell expansion, indicating potential for success in this area.
Where this research is happening
-
Link Biosystems INC.
Irvington, United States Active
Researchers
- Principal investigator: Ronaldson, Kacey — Link Biosystems INC.
- Study coordinator: Ronaldson, Kacey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.