NIH-funded research P01 program project

Improving the prevention of mother-to-child HIV transmission in Malawi

Official title: Implementation Science Core [Parent Title: PREVENTING INFANT INFECTIONS WITH IMPLEMENTATION SCIENCE IN MALAWI]

Funded at Univ of North Carolina Chapel Hill · NIH-11063845 · Data updated 2026-11-12

This study is all about finding better ways to help prevent mothers in Malawi from passing HIV to their babies, making sure that the best methods are actually used in hospitals and clinics.

More Implementation Science research and trials

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startMay 15, 2023
Project endMarch 31, 2028
Funding year2025
Award (this year)$74,022
NIH project number5P01HD112215-03
Project IDNIH-11063845 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are pregnant women living with HIV in Malawi who are at risk of transmitting the virus to their infants.

Less likely to help

Patients who are not pregnant or do not have HIV may not receive any benefit from this research.

What this research studies

This research focuses on enhancing the implementation of effective interventions to prevent the transmission of HIV from mothers to their infants in Malawi. By utilizing implementation science, the project aims to ensure that these interventions are not only developed but also effectively integrated into real-world healthcare settings. The research will involve assessing barriers and facilitators to implementation, developing data collection tools, and monitoring the outcomes of these interventions to maximize their impact on public health.

Why it matters

Potential benefit: If successful, this research could significantly reduce the rates of mother-to-child transmission of HIV, leading to healthier infants and families.

How similar studies have gone: Previous research in implementation science has shown promise in improving health outcomes in similar contexts, indicating that this approach could be effective.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Pence, Brian W — Univ of North Carolina Chapel Hill
  • Study coordinator: Pence, Brian W

Related research

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  • Regional hub to speed up ending HIV with practical science

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.