Improving the preservation of meniscus transplants for knee surgeries
Ice-free Cryopreservation with Nanowarming for Banking of Viable Meniscal Transplants
This study is looking at a new way to keep meniscal transplants safe and healthy for people with serious knee injuries, using special techniques to make sure the tissue stays in great shape for when it's needed.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Clemson University NIH-funded |
| Lab location | 1 site (Clemson, United States) |
| Project ID | NIH-10912648 on NIH RePORTER |
What this research studies
This research focuses on developing a new method for preserving meniscal transplants, which are crucial for patients who have suffered significant knee injuries. The approach involves ice-free cryopreservation combined with nanowarming techniques to maintain the viability and structure of the tissue. By addressing the challenges of preserving these tissues, the research aims to enhance the availability of suitable grafts for transplantation, ultimately improving patient outcomes. The study will explore how to effectively distribute cryoprotectants within the meniscal tissue to prevent damage during the preservation process.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from significant meniscus injuries or those who have undergone meniscus removal and are in need of transplantation.
Not a fit: Patients with minor meniscus injuries or those who do not require surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better preservation methods for meniscal transplants, reducing pain and improving recovery for patients undergoing knee surgeries.
How similar studies have performed: Previous studies have shown promise in using ice-free cryopreservation techniques for preserving living tissues, but this specific application to meniscal transplants is novel.
Where this research is happening
Clemson, United States
- Clemson University — Clemson, United States (Active)
Researchers
- Principal investigator: Wang, Shangping — Clemson University
- Study coordinator: Wang, Shangping
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.