Improving the preservation of kidney transplants using advanced cryoprotectants
Greatly Extended Subzero Ischemic Storage of Renal Allografts Using Novel Bio-inspired Next Generation Cryoprotectants
['FUNDING_SBIR_2'] · X-THERMA INC. · NIH-10895527
This study is looking at new ways to keep kidney transplants safe and healthy for longer periods, which could help more people get the organs they need and recover faster after surgery.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | X-THERMA INC. (nih funded) |
| Locations | 1 site (Hercules, UNITED STATES) |
| Trial ID | NIH-10895527 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the preservation of kidney transplants by using innovative cryoprotectants that allow for extended storage times without freezing. By preventing ischemic damage during the procurement of kidneys, the study aims to improve graft viability, leading to quicker patient recovery and reduced hospital stays. The approach involves pre-clinical testing of these cryoprotectants on porcine kidneys, with the goal of extending the cold ischemia time up to 120 hours. This could significantly change how kidney transplants are managed and increase the availability of organs for patients in need.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals awaiting kidney transplants, particularly those in need of improved organ preservation methods.
Not a fit: Patients who have already received a kidney transplant or those not in need of a transplant may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved outcomes for kidney transplant patients, including faster recovery times and reduced healthcare costs.
How similar studies have performed: Other research has shown promise in organ preservation techniques, but this specific approach using novel cryoprotectants is relatively new and untested in clinical settings.
Where this research is happening
Hercules, UNITED STATES
- X-THERMA INC. — Hercules, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KLINE, MARK A — X-THERMA INC.
- Study coordinator: KLINE, MARK A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.