Improving the placement of MitraClip for heart valve treatment using software.
Software-guided Operative Planning of MitraClip Placement
This study is working on a new tool to help doctors place a device called MitraClip more safely and effectively for older patients with mitral regurgitation who can’t have open-heart surgery, using smart technology to make real-time decisions during the procedure.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | 3dt Holdings, LLC NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-11294378 on NIH RePORTER |
What this research studies
This research focuses on enhancing the placement of the MitraClip, a device used to treat mitral regurgitation, particularly in elderly patients who cannot undergo open-heart surgery. By developing a machine learning-based software tool, the study aims to optimize the placement process by analyzing various factors such as heart pressures and stresses on heart structures. The approach involves creating a comprehensive dataset from existing patient data to inform real-time predictions during the procedure. This innovative method seeks to improve patient outcomes by ensuring safer and more effective device placements.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly patients over 75 years old suffering from moderate to severe mitral regurgitation who are not suitable for traditional surgery.
Not a fit: Patients with mild mitral regurgitation or those who are candidates for open-heart surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for patients with mitral regurgitation, particularly those who are frail or have other health complications.
How similar studies have performed: Other research has shown promise in using machine learning and advanced imaging techniques to improve cardiac procedures, indicating a potential for success in this novel approach.
Where this research is happening
San Diego, United States
- 3dt Holdings, LLC — San Diego, United States (Active)
Researchers
- Principal investigator: Guccione, Julius Matteo — 3dt Holdings, LLC
- Study coordinator: Guccione, Julius Matteo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.