Improving the measurement of Lp(a) levels for better heart disease care
Translating Lp(a) biology to clinical applications
This study is working on better ways to measure Lp(a) levels, which can help identify people at risk for heart disease, so that doctors can provide more accurate care and treatment for those who need it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11055375 on NIH RePORTER |
What this research studies
This research focuses on developing new methods and tools to accurately measure Lp(a) levels, which are important indicators of cardiovascular disease risk. Elevated Lp(a) levels are common and recognized as a significant genetic risk factor for heart conditions. The study aims to create standardized diagnostic methods that can be used in clinical settings, addressing current challenges in measuring Lp(a) due to its complex structure. By improving measurement accuracy, the research seeks to enhance patient care and treatment strategies for those at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with elevated Lp(a) levels who are at risk for cardiovascular diseases.
Not a fit: Patients without elevated Lp(a) levels or those not at risk for cardiovascular diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of cardiovascular disease risk, allowing for better-targeted treatments for patients with elevated Lp(a) levels.
How similar studies have performed: Previous research has indicated that improving diagnostic methods for cardiovascular risk factors can lead to significant advancements in patient care, suggesting a promising outlook for this approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Tsimikas, Sotirios — University of California, San Diego
- Study coordinator: Tsimikas, Sotirios
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.