Improving the measurement of lipids in biological samples
Increasing the Coverage, Sensitivity and Specificity of Rapid Lipidomic Measurements
This study is looking at new ways to better understand fats in our bodies, which play important roles in health and diseases like cancer, so that patients can eventually get more accurate tests and treatments based on their fat profiles.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10914181 on NIH RePORTER |
What this research studies
This research focuses on enhancing the methods used to analyze lipids, which are crucial molecules involved in many biological functions. By employing advanced techniques like ion mobility spectrometry and high-resolution mass spectrometry, the project aims to better separate and characterize various lipid species found in complex biological samples. This improved understanding could lead to more accurate assessments of lipid roles in health and disease, particularly in cancer and other disorders. Patients may benefit from more precise diagnostic tools and treatment strategies based on lipid profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions related to lipid metabolism, such as certain cancers or metabolic disorders.
Not a fit: Patients without lipid-related disorders or those not undergoing treatment for conditions influenced by lipid profiles may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostic tools and targeted therapies for diseases linked to lipid imbalances.
How similar studies have performed: Other research has shown promise in improving lipid analysis techniques, suggesting that advancements in this area could lead to significant breakthroughs.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Baker, Erin S — Univ of North Carolina Chapel Hill
- Study coordinator: Baker, Erin S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.