NIH-funded research R01 grant

Improving the efficiency of CT scans to reduce radiation exposure

Official title: Improving the dose efficiency of photon counting CT

Funded at Mayo Clinic Rochester · NIH-11095889 · Data updated 2026-11-12

This study is working on making CT scans safer by using new technology to reduce the amount of radiation you get during the scan, while still ensuring the images are clear and helpful for doctors.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startJune 1, 2024
Project endMarch 31, 2028
Funding year2025
Award (this year)$362,179
NIH project number5R01EB035553-02
Project IDNIH-11095889 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who require CT imaging for diagnostic purposes.

Less likely to help

Patients who do not need CT scans or those who are contraindicated for imaging procedures may not benefit from this research.

What this research studies

This research focuses on enhancing computed tomography (CT) imaging by developing new technologies that improve the efficiency of photon counting detectors. By re-engineering components of CT scanners, the project aims to significantly reduce the radiation dose patients receive during scans. The researchers will create innovative hardware, such as a lightweight anti-scatter grid, to increase the detection of x-rays and minimize unnecessary radiation exposure. This approach seeks to make CT imaging safer while maintaining high-quality diagnostic capabilities.

Why it matters

Potential benefit: If successful, this research could lead to safer CT scans with lower radiation exposure for patients.

How similar studies have gone: Previous research has shown promise in improving CT imaging techniques, but this specific approach with photon counting detectors is relatively novel.

Where this research is happening

  • Mayo Clinic Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Hsieh, Scott Sigao — Mayo Clinic Rochester
  • Study coordinator: Hsieh, Scott Sigao

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.