Improving the effectiveness of therapeutic peptides using polymers
Optimizing therapeutic peptide presentation within polymers
['FUNDING_OTHER'] · UNIVERSITY OF VIRGINIA · NIH-11066439
This study is exploring a new way to make peptide treatments for diseases like cancer and infections work better and last longer by attaching them to special materials, so patients can get more effective therapies with fewer side effects.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-11066439 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the therapeutic potential of peptides, which are short chains of amino acids that can treat various diseases. The study aims to overcome the challenges of peptide stability and effectiveness in the body by attaching them to polymers, which can prolong their lifespan and improve their delivery. By carefully designing the polymer structure and the way peptides are attached, the research seeks to maximize the benefits of these treatments while minimizing potential side effects. This approach could lead to better therapies for conditions like cancer and infections.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with conditions that could benefit from peptide therapies, such as cancer or infections.
Not a fit: Patients who do not have conditions treatable by peptide therapies may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective peptide-based treatments for a variety of diseases.
How similar studies have performed: Previous research has shown promise in using polymer conjugation to enhance peptide therapies, indicating a potential for success in this approach.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LETTERI, RACHEL — UNIVERSITY OF VIRGINIA
- Study coordinator: LETTERI, RACHEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Amyotrophic Lateral Sclerosis Motor Neuron Disease