Improving the diagnosis and treatment of sepsis in emergency departments

Diagnostic Safety and Quality Optimization in Sepsis (DISQOS)

NIH-funded research University of Michigan at Ann Arbor · NIH-10931492

This study is looking for better ways to help doctors quickly and accurately diagnose sepsis in emergency rooms, so patients can get the right treatment right away and stay safe.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10931492 on NIH RePORTER

What this research studies

This research focuses on enhancing the safety and quality of diagnosing sepsis, a life-threatening condition, in emergency departments. It aims to identify effective practices for accurately diagnosing patients who may have sepsis while minimizing the risks associated with misdiagnosis. By employing a mixed-methods evaluation approach, the research will develop a toolkit to help healthcare providers implement these practices effectively. The ultimate goal is to ensure that patients receive timely and appropriate treatment, reducing the chances of severe complications or death.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who are hospitalized with suspected sepsis and are presenting to emergency departments.

Not a fit: Patients who do not present with symptoms of sepsis or those who are not hospitalized may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of sepsis, significantly improving patient outcomes and reducing mortality rates.

How similar studies have performed: Previous research has shown that improving diagnostic practices in emergency settings can lead to better patient outcomes, indicating that this approach has potential for success.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.