Improving the detection of tooth decay using advanced imaging techniques and AI.
Official title: Improving Caries Diagnosis with Targeted Nanoparticle-Enhanced AI-Assisted Intraoral Imaging
Funded at Greenmark Biomedical, INC. · NIH-11006908 · Data updated 2026-11-12
This study is testing a new camera that uses special tiny particles and smart technology to help dentists spot tooth decay earlier and more accurately, making it easier for you to get the care you need for healthier teeth.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Greenmark Biomedical, INC. NIH-funded |
| Lab location | 1 site (Lansing, UNITED STATES) |
| Project start | April 3, 2025 |
| Project end | April 2, 2026 |
| Funding year | 2025 |
| Award (this year) | $294,632 |
| NIH project number | 1R43DE034324-01 |
| Project ID | NIH-11006908 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals of all ages who are at risk for dental caries, particularly those with early signs of tooth decay.
✕Less likely to help
Patients with no risk of dental caries or those who have already undergone extensive dental treatment may not benefit from this research.
What this research studies
This research aims to enhance the diagnosis of dental caries (tooth decay) by developing an intraoral camera that utilizes targeted nanoparticles and artificial intelligence. The approach involves using a mouth rinse that highlights early active caries lesions, allowing for better visualization during dental examinations. By combining traditional imaging methods with advanced AI algorithms, the goal is to improve the accuracy of caries detection and monitoring, ultimately leading to better patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of tooth decay, reducing complications such as pain and tooth loss.
How similar studies have gone: Previous research has shown promise in using AI and advanced imaging techniques for dental diagnostics, indicating a potential for success in this novel approach.
Where this research is happening
-
Greenmark Biomedical, INC.
Lansing, United States Active
Researchers
- Principal investigator: Jones, Nathan Andrew — Greenmark Biomedical, INC.
- Study coordinator: Jones, Nathan Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.