Improving the design and safety of drug-device combination products

Development of a Combination Product Taxonomy and Comparative Human Factors Testing Method for Drug-Device Combination Products Submitted in an ANDA

NIH-funded research University of Detroit Mercy · NIH-10698013

This study is looking at how to make the designs of certain drug-device products safer and more effective, especially for those trying to get approved by the FDA, so that patients can have better access to the medications they need.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Detroit Mercy NIH-funded
Lab location1 site (Detroit, United States)
Project IDNIH-10698013 on NIH RePORTER

What this research studies

This research focuses on enhancing the evaluation of user interface designs for drug-device combination products, particularly those seeking FDA approval through the ANDA pathway. By analyzing design differences that may affect the safety and effectiveness of these products, the research aims to develop a systematic approach to identify potential use errors. The project includes gathering insights from stakeholders, creating a visual taxonomy for design attributes, and establishing methods for comparative analysis between generic and reference products. Ultimately, this work seeks to improve patient access to safe and effective medications.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients who use or may use drug-device combination products, particularly those that are generic.

Not a fit: Patients who do not use drug-device combination products or those who are not involved in the regulatory approval process may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective drug-device combination products, improving patient outcomes.

How similar studies have performed: While this approach is innovative, similar research has shown promise in improving user interface designs in medical devices, indicating potential for success.

Where this research is happening

Detroit, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.