Improving the delivery of fluorinated compounds for better drug development
Taming Fluorine: Metal-Organic Frameworks for the Heterogeneous Delivery of Fluorinated Building Blocks
['FUNDING_OTHER'] · CORNELL UNIVERSITY · NIH-10876279
This study is exploring new ways to make safer and more effective medicines by using special materials that help control how certain helpful chemicals are released or react, which could lead to better treatments for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-10876279 on ClinicalTrials.gov |
What this research studies
This research focuses on overcoming challenges in creating fluorinated molecules that can enhance drug effectiveness. By using innovative porous materials, the project aims to control the reactivity of fluorinated agents, making them safer and more stable for use in pharmaceuticals. The approach involves developing nanomaterials that can either release these agents in a controlled manner or facilitate chemical reactions within their structure. This could lead to the creation of new therapeutic compounds with improved properties.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that could benefit from new fluorinated pharmaceutical agents.
Not a fit: Patients who are not seeking new treatment options or those with conditions that do not involve fluorinated compounds may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective medications with enhanced stability and biological activity.
How similar studies have performed: While the approach of using metal-organic frameworks is relatively novel, similar strategies in materials science have shown promise in enhancing drug delivery and stability.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MILNER, PHILLIP JOHN — CORNELL UNIVERSITY
- Study coordinator: MILNER, PHILLIP JOHN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.