Improving the consistency of breast MRI images
Harmonization of breast MRI data
This study is working on improving breast MRI images so that doctors can better compare and analyze them, which will help in diagnosing tumors and understanding cancer risk for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10892247 on NIH RePORTER |
What this research studies
This research focuses on addressing the inconsistencies in breast MRI images caused by different scanners and acquisition parameters. By developing three new harmonization methods, the project aims to enable more accurate quantitative analysis of breast MRIs, which can help in diagnosing tumors, predicting patient outcomes, and assessing cancer risk. The approach involves transforming images from various sources to ensure they can be reliably compared and analyzed. This is particularly important as breast tissue is complex and varies significantly among patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing breast MRI scans for tumor diagnosis or cancer risk assessment.
Not a fit: Patients who have already received definitive treatment for breast cancer and are not undergoing further imaging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment outcomes for patients with breast cancer.
How similar studies have performed: While similar harmonization efforts have been attempted for other organs, particularly the brain, this specific approach for breast MRI is novel and untested.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Mazurowski, Maciej a. — Duke University
- Study coordinator: Mazurowski, Maciej a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.