Improving the bond between dental materials and teeth to prevent decay

Peptide-Polymer Engineering Dentin/Adhesive Interfacial Bond Integrity

NIH-funded research University of Kansas Lawrence · NIH-10895331

This study is working on creating stronger dental adhesives that stick better to your teeth, so your dental work lasts longer and you won't need as many repairs in the future.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kansas Lawrence NIH-funded
Lab location1 site (Lawrence, United States)
Project IDNIH-10895331 on NIH RePORTER

What this research studies

This research focuses on enhancing the bond integrity between dental adhesives and tooth dentin to reduce the need for repeated dental restorations. It aims to develop new polymers that can withstand the harsh conditions of the oral environment, including acids and bacteria, which often lead to the failure of dental composites. By addressing the vulnerabilities at the interface of the tooth and adhesive, the project seeks to create a more durable and effective solution for dental restorations. Patients may benefit from improved dental treatments that last longer and reduce the risk of tooth loss.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who require dental restorations, particularly those with a history of composite failures.

Not a fit: Patients who have no need for dental restorations or those with underlying conditions that prevent standard dental procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to longer-lasting dental restorations and improved oral health for patients.

How similar studies have performed: Previous research has shown promise in developing improved dental materials, indicating that this approach may lead to significant advancements in dental care.

Where this research is happening

Lawrence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.