Improving the analysis of glycoproteins to understand diseases better
Capturing Low-Abundance Glycopeptides for Decoding the Glycoproteome
['FUNDING_R01'] · GEORGIA INSTITUTE OF TECHNOLOGY · NIH-10669037
This study is working on a new way to find important proteins in the body that can help us understand diseases better, which could lead to improved tests and treatments for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10669037 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the analysis of glycoproteins, which are crucial for understanding cell development and disease. By developing a new method to capture low-abundance glycopeptides, the project aims to provide a comprehensive view of protein glycosylation using advanced mass spectrometry techniques. This approach will help identify glycoproteins that could serve as biomarkers for various diseases, potentially leading to better diagnostic and therapeutic strategies. Patients may benefit from improved understanding of their conditions through the insights gained from this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to glycoprotein abnormalities, such as certain cancers or metabolic disorders.
Not a fit: Patients with conditions unrelated to glycoprotein function or those not affected by glycosylation processes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the identification of new biomarkers for diseases, improving diagnosis and treatment options for patients.
How similar studies have performed: Previous research has shown promise in analyzing glycoproteins, but this specific approach to capturing low-abundance glycopeptides is innovative and less tested.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA INSTITUTE OF TECHNOLOGY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WU, RONGHU — GEORGIA INSTITUTE OF TECHNOLOGY
- Study coordinator: WU, RONGHU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer