Improving the analysis of brain images for Alzheimer's disease
Bayesian Object-Oriented Modeling of Multi-Modal Imaging Data
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10991810
This study is working on new ways to look at brain scans from people with Alzheimer's and similar conditions to better understand how these diseases affect the brain, which could help improve care and treatment for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10991810 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced statistical methods to analyze brain images from patients with Alzheimer's disease and other neurodegenerative disorders. By integrating different types of imaging data, the project aims to enhance the understanding of how these diseases disrupt brain structure and connectivity. The approach utilizes hierarchical Bayesian models to improve the accuracy and efficiency of clinical interpretations, which could lead to better monitoring and treatment strategies for patients. The research addresses significant challenges in current methodologies, aiming to provide a more comprehensive view of brain health in the context of aging and cognitive decline.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or other neurodegenerative disorders who are undergoing imaging assessments.
Not a fit: Patients with non-neurodegenerative cognitive impairments or those not undergoing brain imaging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients with Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in using Bayesian methods for analyzing complex medical data, indicating potential for success in this novel approach.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHEFFLER, AARON WOLFE — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: SCHEFFLER, AARON WOLFE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: advanced disease, Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease