Improving tests to understand how brain circuits control attention and cognition
Optimization of the 5-choice continuous performance test to reveal a parietal-anterior cingulate-claustrum circuit underlying cognitive control and attention
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11078747
This study is working to improve a brain test that measures attention and focus, using touchscreens to make it easier for people with mental health conditions to take, while also looking at how the brain works during the test to help find better treatments.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11078747 on ClinicalTrials.gov |
What this research studies
This research aims to enhance a specific cognitive test known as the 5-choice continuous performance test (5C-CPT) to better understand the brain circuits involved in cognitive control and attention. By optimizing this test for use with touchscreen technology, researchers hope to create a more effective tool for assessing cognitive function across various psychiatric disorders. The study will involve both animal models and human participants, utilizing advanced imaging techniques like EEG and fMRI to validate the brain circuits engaged during the test. This approach seeks to provide a clearer understanding of cognitive dysfunction and improve treatment strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with cognitive impairments related to psychiatric disorders.
Not a fit: Patients without cognitive dysfunction or those not diagnosed with psychiatric conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for cognitive dysfunction in psychiatric patients.
How similar studies have performed: While there have been attempts to study cognitive control and attention, this specific approach using the optimized 5C-CPT is relatively novel and has not been extensively tested.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YOUNG, JARED WILLIAM — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: YOUNG, JARED WILLIAM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.