Improving tests for tuberculosis in young children
Novel and Optimized Diagnostics for Pediatric TB
This study is working on better ways to test for tuberculosis in young children under five, especially those in Uganda who might also be dealing with HIV, to make sure they get the right diagnosis and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-10828832 on NIH RePORTER |
What this research studies
This research focuses on developing new and optimized diagnostic tests for tuberculosis (TB) specifically in children under five years old. The study will involve well-characterized cohorts of children in Uganda and utilize existing biorepositories from previous pediatric diagnostic studies in Kenya. By addressing the challenges of diagnosing pediatric TB, especially in high-burden areas, the research aims to enhance the accuracy of TB detection in young patients, particularly those who are HIV-infected or exposed. The methodology includes evaluating the sensitivity of new diagnostic approaches compared to traditional methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under five years old, particularly those who are HIV-infected or have been exposed to HIV.
Not a fit: Patients over the age of five or those without any risk factors for TB or HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and accessible TB diagnostics for young children, potentially reducing misdiagnosis and improving treatment outcomes.
How similar studies have performed: Previous research has shown that innovative diagnostic approaches can improve TB detection in adults, but this specific focus on pediatric TB diagnostics is relatively novel.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Ellner, Jerrold J. — Rutgers Biomedical and Health Sciences
- Study coordinator: Ellner, Jerrold J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.