Improving tests for biomarkers of neurodegenerative diseases like Alzheimer's
Highly sensitive immunoassay for determination of biomarkers for neurodegenerative diseases
This study is working on a new way to improve tests that look for important signs of Alzheimer's disease in your spinal fluid, making it easier to catch the disease early and track how it's changing over time.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Allied Innovative Systems, LLC NIH-funded |
| Lab location | 1 site (Chatham, UNITED STATES) |
| Project ID | NIH-10837872 on NIH RePORTER |
What this research studies
This research focuses on enhancing the sensitivity of existing tests used to detect biomarkers associated with neurodegenerative diseases, particularly Alzheimer's Disease. By developing a new method called photochemical signal amplification, the researchers aim to make it easier to identify low levels of critical proteins in the cerebrospinal fluid that indicate the presence of Alzheimer's. This could lead to earlier and more accurate diagnoses, allowing for better monitoring of disease progression. The approach involves refining enzyme-linked immunosorbent assays (ELISA), which are commonly used in medical testing but often lack the sensitivity needed for early detection of these biomarkers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for or showing early signs of Alzheimer's Disease.
Not a fit: Patients with advanced Alzheimer's Disease or those without any neurodegenerative conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and earlier diagnoses of Alzheimer's Disease, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in enhancing biomarker detection methods, but this specific approach is novel and untested.
Where this research is happening
Chatham, UNITED STATES
- Allied Innovative Systems, LLC — Chatham, United States (Active)
Researchers
- Principal investigator: Bystryak, Simon — Allied Innovative Systems, LLC
- Study coordinator: Bystryak, Simon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.