Improving technologies to understand the protein degradation system in cells
Supplement: Advancing Proteomics Technologies to Decipher the Ubiquitin-Proteasome System
This study is working on improving technology to better understand how our bodies break down proteins, which is important for keeping us healthy, and it could help find new treatments for diseases like cancer and conditions that affect the brain.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11099177 on NIH RePORTER |
What this research studies
This research focuses on advancing proteomics technologies to better understand the ubiquitin-proteasome system, which is crucial for protein degradation in cells. By enhancing these technologies, the research aims to provide deeper insights into how proteins are broken down and regulated within the body. Patients may benefit from this research as it could lead to new treatments for diseases related to protein mismanagement, such as cancer and neurodegenerative disorders. The approach involves sophisticated techniques to analyze protein interactions and functions, which could ultimately improve our understanding of various health conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to protein mismanagement, such as certain cancers or neurodegenerative diseases.
Not a fit: Patients with conditions unrelated to protein degradation or those not experiencing any protein-related disorders may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases caused by protein degradation issues.
How similar studies have performed: Other research has shown success in using advanced proteomics technologies to understand cellular processes, indicating that this approach has potential for impactful findings.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Huang, Lan — University of California-Irvine
- Study coordinator: Huang, Lan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.