Improving tDCS Brain Stimulation for Depression
Optimization of tDCS brain network engagement in depression
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11282269
This project explores how a gentle brain stimulation called tDCS affects brain activity in people with depression to make treatments more effective.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11282269 on ClinicalTrials.gov |
What this research studies
We are looking at how a non-invasive brain stimulation called transcranial direct current stimulation (tDCS) works in the brains of people with depression. Depression is linked to certain brain areas being over or underactive, and tDCS aims to balance this activity. We will use fMRI scans while people receive tDCS to see how the stimulation changes brain activity and connections. We also want to see if doing a memory task during tDCS can make the treatment even more powerful.
Who could benefit from this research
Good fit: Individuals diagnosed with depression who are interested in non-invasive brain stimulation therapies may be ideal candidates.
Not a fit: Patients who do not have depression or are not suitable for tDCS or fMRI procedures would likely not benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more precise and effective tDCS treatments for individuals living with depression.
How similar studies have performed: While tDCS is an investigational treatment, previous work in model systems suggests that combining tDCS with cognitive tasks might amplify its effects.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOG, MAYANK ANANT — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: JOG, MAYANK ANANT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.