Improving targeted therapies for cancer treatment
Official title: Expanding the design space of protein-small molecule conjugates
Funded at Smith College · NIH-10729980 · Data updated 2026-11-12
This study is looking at new ways to create special treatments that combine proteins and small molecules to help cancer patients get more effective and personalized therapies with fewer side effects.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Smith College NIH-funded |
| Lab location | 1 site (Northampton, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $398,833 |
| NIH project number | 1R15GM151648-01 |
| Project ID | NIH-10729980 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with solid tumors who may benefit from advanced targeted therapies.
✕Less likely to help
Patients with hematological cancers may not benefit directly from this research as it focuses on solid tumors.
What this research studies
This research focuses on enhancing the design of protein-small molecule conjugates to improve targeted therapy and drug delivery for cancer patients. By exploring new combinations and components, the research aims to overcome existing challenges in treating solid tumors and expand access to precision medicine. The approach involves creating and validating innovative conjugate designs that could lead to better treatment outcomes with fewer side effects. Patients may benefit from more effective and personalized treatment options based on the molecular characteristics of their cancers.
Why it matters
Potential benefit: If successful, this research could provide patients with more effective and personalized cancer treatments that minimize side effects.
How similar studies have gone: Previous research has shown success with antibody-drug conjugates in cancer therapy, indicating potential for this novel approach.
Where this research is happening
-
Smith College
Northampton, United States Active
Researchers
- Principal investigator: Moore, Sarah J. — Smith College
- Study coordinator: Moore, Sarah J.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.