Improving symptom management and physical activity for stem cell transplant patients
Randomized Controlled Trial of a Hybrid-Delivered Cognitive Behavioral Symptom Management and Activity Coaching Intervention for Stem Cell Transplant Patients
This study is testing a new program called Step Up to help people who have had a stem cell transplant feel better and get moving again by combining in-person support and mobile health tools, so they can better manage symptoms like fatigue and pain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10937615 on NIH RePORTER |
What this research studies
This research focuses on helping patients who have undergone hematopoietic stem cell transplant (HCT) manage their symptoms and increase their physical activity through a hybrid approach that combines in-person sessions and mobile health technology. The intervention, called Step Up, includes cognitive behavioral coping skills training and activity coaching led by occupational therapists. Patients will receive both in-person and video sessions to support their recovery and enhance their ability to cope with fatigue, pain, and distress. The study aims to determine the effectiveness of this intervention compared to standard care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently undergone hematopoietic stem cell transplant and are experiencing symptoms that hinder their physical activity.
Not a fit: Patients who are not eligible for stem cell transplant or those who do not experience significant symptoms affecting their physical activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for stem cell transplant patients by enhancing their physical activity and reducing debilitating symptoms.
How similar studies have performed: Previous studies have shown promising results with similar hybrid interventions, indicating potential for success in this approach.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kelleher, Sarah — Duke University
- Study coordinator: Kelleher, Sarah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.