Improving swallowing function in patients with Alzheimer's and related dementias

Who could benefit from this research

What this research studies

This research focuses on developing new rehabilitative interventions to help patients with Alzheimer's Disease and related dementias who experience dysphagia, or swallowing difficulties. The project aims to train a speech-language pathologist to create effective treatments that can improve swallowing function and reduce health risks associated with dysphagia. Current methods often fail to provide lasting benefits, so the research will explore innovative approaches like progressive-resistance lingual strengthening and saliva substitutes. By addressing the underlying issues of swallowing dysfunction, the goal is to enhance the quality of life for these patients.

Why it matters

Where this research is happening

• University of Wisconsin-Madison
  Madison, United States Active

Researchers

• Principal investigator: Rogus-Pulia, Nicole M — University of Wisconsin-Madison
• Study coordinator: Rogus-Pulia, Nicole M

Related research

Other NIH-funded projects on the same topics.

• Swallowing changes and causes of swallowing problems in Alzheimer's disease

  Following people with Alzheimer's over time to understand how their swallowing changes and what factors lead to swallowing problems.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11321295

• Understanding swallowing difficulties in Alzheimer's disease

  This study is looking at the swallowing problems that people with Alzheimer's and similar conditions often face, to understand what causes these issues and how they change over time, so we can find better ways to help manage them and prevent serious health problems.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11079467

• Evaluating and predicting swallowing improvement in hospitalized Alzheimer's patients

  This study is looking at how to help patients with Alzheimer's and related dementias who have trouble swallowing, by using a special computer program to predict which patients might get better before they leave the hospital, so that doctors can give them the best care and diet to improve their eating and overall well-b

  NIH research Feinstein Institute for Medical Research · Manhasset, United States · NIH-11054066

• Engaging underrepresented individuals with Alzheimer's disease in swallowing research

  This study is looking for ways to help people with Alzheimer's and related dementias who have trouble swallowing by teaming up with community groups to make sure everyone gets a chance to participate, so we can find better treatments that improve their swallowing and overall well-being.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-10841340

• Understanding how brain activity changes may drive Alzheimer’s disease progression in a mouse model

  Researchers are testing how changes in brain signals and protein cleanup processes affect the development of Alzheimer’s disease in mice.

  NIH research Nathan S. Kline Institute for Psych Res · Orangeburg, United States · NIH-11627965

• Thiamine-boosting therapy for Alzheimer’s: understanding how benfotiamine may reduce harmful AGE in DP patients

  A medication-based approach using high-dose vitamin B1 (benfotiamine) is studied to help people with Alzheimer's by reducing harmful sugar-related molecules.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11627145

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.