Improving surgical planning for bicuspid aortic valve repair using advanced imaging techniques
4D Multimodal Image-Based Modeling for Bicuspid Aortic Valve Repair Surgery
This study is working on improving how doctors plan surgery for young adults with a bicuspid aortic valve and aortic regurgitation by using advanced 4D imaging to get a clearer picture of the heart's structure, helping to create personalized treatment plans.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11086051 on NIH RePORTER |
What this research studies
This research focuses on enhancing the surgical planning process for bicuspid aortic valve (BAV) repair in young adults suffering from aortic regurgitation. By developing a multimodal 4D imaging and modeling platform, the project aims to provide detailed pre-operative assessments of the valve's anatomy and dynamics. This approach will allow for more accurate identification of defects that contribute to aortic regurgitation, ultimately leading to tailored surgical strategies. The research involves creating automated algorithms to analyze various imaging modalities, ensuring that surgical interventions are based on precise anatomical data.
Who could benefit from this research
Good fit: Ideal candidates for this research are young adults diagnosed with aortic regurgitation due to a bicuspid aortic valve.
Not a fit: Patients with other types of aortic valve conditions or those who are not candidates for surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized surgical treatments for patients with bicuspid aortic valves, improving their outcomes.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cardiac surgery, indicating that this approach could yield significant advancements in surgical planning.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Pouch, Alison Marie — University of Pennsylvania
- Study coordinator: Pouch, Alison Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.