NIH-funded research NIH-funded research

Improving surgery for congenital aortic valve disease in children

Official title: Optimizing Congenital Aortic Valve Surgery with Simulation-Guided Design

Funded at Stanford University · NIH-10949651 · Data updated 2026-11-12

This study is looking at ways to make heart surgeries safer and more successful for kids with congenital aortic valve disease by testing new techniques and methods, so they can have better outcomes and fewer complications.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startAugust 16, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$181,392
NIH project number1K25HL175208-01
Project IDNIH-10949651 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who are diagnosed with congenital aortic valve disease and may require surgical intervention.

Less likely to help

Patients with congenital heart defects other than aortic valve disease may not benefit from this specific research.

What this research studies

This research focuses on enhancing surgical outcomes for children with congenital aortic valve disease, a common heart defect. By using advanced simulations and modeling techniques, the project aims to determine the best surgical approaches, including innovative valve repair and replacement methods. The research will involve both laboratory studies and clinical applications to ensure that findings can be effectively translated into real-world surgical practices. The goal is to reduce complications and improve the overall success of surgeries for affected children.

Why it matters

Potential benefit: If successful, this research could lead to better surgical outcomes and improved quality of life for children with congenital aortic valve disease.

How similar studies have gone: Previous research has shown promise in using simulation-guided approaches for surgical planning, indicating potential for success in this novel application.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Kaiser, Alexander D — Stanford University
  • Study coordinator: Kaiser, Alexander D

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.