Improving stroke treatment by assessing brain blood flow during procedures
Assessing brain perfusion using IPEN during intra-arterial stroke intervention
This study is testing a new way to check blood flow in the brain during a procedure that removes clots from the brain after a stroke, to help doctors choose the best patients for treatment and improve their chances of recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11080870 on NIH RePORTER |
What this research studies
This research focuses on enhancing the treatment of ischemic stroke, which is a leading cause of long-term disability. It aims to develop a new method called IPEN v2 for real-time brain perfusion imaging during endovascular mechanical thrombectomy (EVT), a procedure that removes blood clots from the brain. By assessing blood flow and the viability of brain tissue, the research seeks to improve patient selection for EVT, ensuring that only those who will benefit from the procedure are treated. This approach could lead to better outcomes and reduced risks associated with stroke interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing an ischemic stroke who are eligible for endovascular mechanical thrombectomy.
Not a fit: Patients who have experienced hemorrhagic strokes or those who are not candidates for EVT may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the safety and effectiveness of stroke treatments, leading to better recovery outcomes for patients.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for stroke management, indicating that this approach could be a meaningful advancement in the field.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Taguchi, Katsuyuki — Johns Hopkins University
- Study coordinator: Taguchi, Katsuyuki
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.