Improving stroke risk prediction for patients with atrial fibrillation.

Personalized Stroke Risk Stratification in Atrial Fibrillation: Integrating Probabilistic Graphical Models and High-dimensional EHR Data for Interpretable Prognosis

NIH-funded research Denver Health and Hospital Authority · NIH-11025957

This study is working on a new tool to help predict stroke risk for people with atrial fibrillation by looking at both health and social factors, so that doctors can better tailor prevention strategies just for you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDenver Health and Hospital Authority NIH-funded
Lab location1 site (Denver, United States)
Project IDNIH-11025957 on NIH RePORTER

What this research studies

This research aims to create a personalized tool for predicting stroke risk in patients with atrial fibrillation (AF) by integrating advanced data analysis techniques. It will explore new risk factors, including social determinants of health, and combine them with existing factors using machine learning to enhance understanding and explainability. The goal is to develop a tool that can be used across different healthcare systems to improve stroke prevention strategies tailored to individual patient needs.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with atrial fibrillation who may be at risk for stroke.

Not a fit: Patients without atrial fibrillation or those who do not have risk factors for stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate stroke risk assessments and better prevention strategies for patients with atrial fibrillation.

How similar studies have performed: Previous research has shown promise in using machine learning and social determinants of health to improve risk stratification in various medical conditions, indicating potential success for this approach.

Where this research is happening

Denver, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.