Improving strategies to prevent mother-to-child transmission of HIV
Official title: Informing optimal investments along the preconception to postpartum eMTCT continuum
Funded at University of Minnesota · NIH-10916709 · Data updated 2026-11-12
This study is looking at ways to help prevent mothers from passing HIV to their babies by testing different support strategies for women before, during, and after pregnancy, with the goal of finding the best and most affordable options for use in sub-Saharan Africa.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 22, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $539,000 |
| NIH project number | 1DP1HD115428-01 |
| Project ID | NIH-10916709 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women or women planning to become pregnant in sub-Saharan Africa who are at risk of HIV infection.
✕Less likely to help
Patients who are not pregnant or not planning to become pregnant, as well as those outside the targeted geographic region, may not benefit from this research.
What this research studies
This research investigates how to enhance the prevention of mother-to-child transmission (eMTCT) of HIV by evaluating various interventions alongside maternal antiretroviral therapy (ART). It employs simulation-based modeling and decision science to identify the most effective and economically feasible strategies for implementation in sub-Saharan Africa. The goal is to create a comprehensive toolbox of interventions that support women from preconception through postpartum, ultimately aiming to reduce new infections among infants. By focusing on both upstream and downstream interventions, the research seeks to inform health policy and improve outcomes for mothers and children.
Why it matters
Potential benefit: If successful, this research could significantly reduce the number of new HIV infections in infants, improving health outcomes for children born to HIV-positive mothers.
How similar studies have gone: Previous research has shown success in using decision science and modeling to improve HIV treatment strategies, indicating that this approach has the potential for significant impact.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Duarte, Horacio Adrian — University of Minnesota
- Study coordinator: Duarte, Horacio Adrian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.