Improving spinal cord injury recovery by targeting specific cell types
Official title: Targeting Cell-Type Specific Disease Phenotypes to Promote CNS Repair
Funded at University of Miami School of Medicine · NIH-11082502 · Data updated 2026-11-12
This study is looking for new ways to help people with spinal cord injuries by finding the right types of cells to target and creating special treatments that can be delivered directly to those cells to improve recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | August 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,181,130 |
| NIH project number | 5RM1NS133003-03 |
| Project ID | NIH-11082502 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced spinal cord injuries and are seeking innovative treatment options.
✕Less likely to help
Patients with conditions unrelated to spinal cord injuries may not benefit from this research.
What this research studies
This research focuses on developing new therapies for spinal cord injury (SCI) by identifying and targeting specific cell types involved in the injury site. Using advanced techniques like single-cell transcriptomics and proteomics, the team aims to discover compounds that can reverse disease effects in a tailored manner. Additionally, they will create a specialized drug delivery system that ensures these compounds are delivered effectively to the right cells at the injury site, enhancing the potential for recovery.
Why it matters
Potential benefit: If successful, this research could lead to effective treatments that promote recovery from spinal cord injuries.
How similar studies have gone: Previous research has shown promise in targeting specific cell types for therapeutic purposes, indicating potential success for this novel approach.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Lee, Jae K — University of Miami School of Medicine
- Study coordinator: Lee, Jae K
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.