Improving speech recovery for people with aphasia after stroke

Speech Entrainment for Aphasia Recovery (SpARc)

NIH-funded research Medical University of South Carolina · NIH-10690454

This study is testing a new therapy called speech entrainment therapy (SET) to help people with non-fluent aphasia, which can happen after a stroke, by using a fun audio-visual tool on a laptop to improve their speaking and communication skills.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-10690454 on NIH RePORTER

What this research studies

This research investigates a new therapy called speech entrainment therapy (SET) designed to help individuals with non-fluent aphasia, a common language impairment following a stroke. Participants will engage with an audio-visual model on a laptop that guides their speech, aiming to improve their fluency and communication abilities. The study will assess the effectiveness of this therapy through a controlled clinical trial, measuring improvements in spontaneous speech and overall language use. By focusing on practical language skills, the research seeks to enhance the quality of life for those affected by aphasia.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been diagnosed with non-fluent aphasia following a stroke and are experiencing challenges in speech production.

Not a fit: Patients who do not have aphasia or those with other forms of speech or language impairments unrelated to stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve speech fluency and communication skills for patients with aphasia, leading to better social interactions and quality of life.

How similar studies have performed: Preliminary studies have shown promising results with similar approaches, indicating that speech entrainment therapy may effectively improve speech fluency in individuals with non-fluent aphasia.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.